Auto-antibodies to protein Z in patients undergoing off-pump coronaryartery bypass surgery – preliminary results
Diagnostyka Laboratoryjna（2019）
摘要
Background: Considerable attention has been focused over the past several years on the protein Z (PZ) system. However, little is known about the role of auto-antibodies to PZ (anti-PZ) in cardiac surgery patients.
Aim: In the present pilot study, we investigated plasma levels of anti-PZ in patients undergoing off-pump coronary artery bypass (OPCAB) surgery.
Material and methods: Thirty patients with coronary artery disease scheduled for OPCAB surgery were enrolled in this study. Plasma levels of anti-PZ IgM and anti-PZ IgG were measured before surgery and one week after surgery using enzyme-linked immunosorbent assay.
Results: None of the subjects were shown to have positive results for anti-PZ IgM and anti-PZ IgG either before and one week after OPCAB surgery.
Conclusions: These results suggest that anti-PZ autoantibodies are not an effective component of the PZ system in OPCAB patients.
更多Aim: In the present pilot study, we investigated plasma levels of anti-PZ in patients undergoing off-pump coronary artery bypass (OPCAB) surgery.
Material and methods: Thirty patients with coronary artery disease scheduled for OPCAB surgery were enrolled in this study. Plasma levels of anti-PZ IgM and anti-PZ IgG were measured before surgery and one week after surgery using enzyme-linked immunosorbent assay.
Results: None of the subjects were shown to have positive results for anti-PZ IgM and anti-PZ IgG either before and one week after OPCAB surgery.
Conclusions: These results suggest that anti-PZ autoantibodies are not an effective component of the PZ system in OPCAB patients.
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关键词
coronary artery bypass surgery,protein,auto-antibodies,off-pump
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