Cardiac Enhancer Variants at the Mtss1 Locus Are Associated with Smaller, More Contractile Hearts

Megan F. Burke,Michael P. Morley,Yifan Yang,Theodore G. Drivas,Dongwook Choe,Sharlene Day,Kiran Musunuru,Mingyao Li,Marylyn Ritchie,Thomas P. Cappola

CIRCULATION（2021）

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摘要

Introduction: Variants at the MTSS1 locus influence cardiac structure, function, and failure in multiple genome wide association studies (GWAS), yet the genetic mechanisms remain unclear. We previo...

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关键词

cardiac enhancer variants,mtss1 locus,more contractile hearts

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