A handheld confocal microscope with MEMS-based flat-field scanning for fluorescence-guided surgery

Linpeng Wei,Chengbo Yin,Sanjeewa Abeytunge,Gary Peterson,Michael J. Mandella,Milind Rajadhyaksha,Nader Sanai,Jonathan T. C. Liu

Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) (2019), paper DS2A.5（2019）

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Abstract

We developed a handheld line-scanned dual-axis confocal microscope for real-time optical biopsy. The device utilizes a novel MEMS-based scanning mechanism for field-flattening, and provides high-speed (16 Hz) fluorescence imaging with sub-nuclear resolution in tissue.

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Key words

handheld confocal microscope,mems-based,flat-field,fluorescence-guided

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