Comparative evaluation of biofilm formation among three differently treated surface on titanium samples

Background: Use of osseointegrated oral implants has been an excellent method for replacement of missing teeth. Biofilm formation on oral implants can cause inflammation of peri-implant tissues, which can affect the long-term success of osseointegrated implants. Aims and Objectives: Comparative evaluation of biofilm formation among three differently treated surface on titanium samples Methodology: Samples were blasted and later loaded with gentamicin drug by vacuum drying and evaluation of the strains was done for biofilm. Bacterial adhesion was evaluated on time intervals of 0 h, 1 h, 4 h 24 h, and 48 h. Results: Bacterial adhesion was sequentially increasing in polished samples. Initial bacterial adhesion was more on surface modified samples when compared to polished samples in the 1st h. Bacterial adhesion was retarded in gentamicin-coated hydroxyapatite (HA)-blasted samples up to 24 h. Bacterial adhesion was considerably less on TiO2-blasted samples up to 48 h. Conclusion: Implant surface modified with TiO2and gentamicin showed delayed biofilm formation even up to 48 h. Surface modification with HA has gained considerable osteoconductive surface which is a boon for the production of future implants with less expense; however, further studies are to be carried out to prove its efficacy.