Abstract 14476: Effects of Encaleret on Corrected QT Interval in Autosomal Dominant Hypocalcemia Type 1: Early Results From an Ongoing Phase 2b, Open-Label, Dose-Ranging Study

Iris R Hartley,Rachel I Gafni,Kelly Lauter Roszko,Karen A Pozo,Michael T. Collins,Edward F. Nemeth,Ramei Sani-Grosso,Ananth Sridhar, Lyndsay M. Stapleton,Mary Scott Roberts,Jonathan C. Fox

Circulation（2021）

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Introduction: Autosomal dominant hypocalcemia type 1 (ADH1) is caused by gain-of-function variants of the calcium-sensing receptor (CaSR) gene, resulting in receptor proteins with increased sensiti...

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