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Clinical Implications of Integrating Polygenic Risk Into Established Cardiovascular Disease Risk Scores

Fernando Riveros-Mckay,Saskia Selzam,Priyanka Seth,Rachel Moore,William A. Tarran,Jack W. O'Sullivan,Euan A. Ashley,Gilean McVean, Vincent Plagnol,Peter Donnelly,Michael E. Weale

Circulation（2021）

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Abstract
Risk-guided intervention in the US, informed by the pooled cohort equations (PCE) risk calculator, is the accepted practice for prevention of atherosclerotic cardiovascular disease (ASCVD). We rece...
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Key words
polygenic risk,cardiovascular disease,clinical implications
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