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Neonatal Buzağılarda İki Farklı İmmunomodülatörün Buzağı İshalleri Üzerine Etkileri

Kocatepe Veterinary Journal(2021)

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Abstract
In the study, 18 new calves were used. The calves were divided into 3 groups in each group after the first controls. One of the groups was defined as control group (Group 1) and the other two groups as study groups (Group 2 and Group 3). Two different commercial immunomodulatory preparations were given to Group 2 and Group 3 while physiological saline was given for the placebo to the Control Group. Blood samples were collected at days 0, 3, 7, and 15 for immunoglobulin G (Ig) measurement and at days 0, 7, and 15 for hematological measurements. In hematological examination; Leukocyte (WBC), Lymphocyte (LENF), Monocyte (MON), Granulocyte (GRAN), Lymphocyte percentage (LENF%), Monocyte percentage (MON%), Granulocyte percentage (GRAN%), Red Blood Cells (RBC), Hemoglobin (HGB) Hematocrit (HCT), Mean Cell Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Cell Hemoglobin Concentration (MCHC), Red Cell Distribution Width (RDW), Thrombocyte (PLT), Mean Platelet Volume (MPV), Thrombocyte Distribution Range (PDW) was measured. Immunoglobulin G levels were measured in the sera obtained from the blood samples. As a result of the study, IgG level was determined high on the 3rd day in Group 3. In addition, IgG levels decreased in the fastest way on control group especially on the 3rd day. We think that the newborn calves have an effect on the immunoglobulin G levels in the first fifteen days after birth.
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Key words
calf diarrhea,neonatal calves,different immunomodulators
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