Drug Delivery: Injectable Drug-Releasing Microporous Annealed Particle Scaffolds for Treating Myocardial Infarction (Adv. Funct. Mater. 43/2020)
Advanced Functional Materials(2020)
Abstract
In article number 2004307, Randall Lee, Dino Di Carlo, Song Li, and co-workers report a novel multi-modal drug-releasing microstructured hydrogel (drugMAP) system that is created in a microfluidic device. The drugMAP is loaded with nanoparticles that release a cocktail containing a cAMP activator and a TGF-β inhibitor, which significantly enhances left ventricular function in infarcted hearts.
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Key words
microporous annealed particle scaffolds,myocardial infarction,injectable,delivery
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