Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network

Background: Famotidine is one of gastrointestinal drugs which is used by drink or injection, soluble in acids and weakly dissolved in water. It has the effect of reducing gastric secretion by inhibiting histamine at the H2 receptor in the gastric mucosa wall, decreasing the secretion of HCl in gastric juice, the healing of gastric ulcers. Manufacture, In vitro Characterization And In vivo Bioavailability Evaluation of famotidine Loaded 3D-Nano-Cellulose Network (3DNC) by bacteria and Used for Oral Administration. Methods: Famotidine is a gastrointestinal H2-receptor antagonist drug with low bioavailability (40-45%). 3DNC can be produced from bacteria living in fermented green tea and is the material containing nano-sized fibers which is capable of loading Famotidine to form a prolonged release therapy to improve drug bioavailability. Results: This research has been produced 3DNC materials from bacteria in some nutrient media; it has used scanning electron microscope (SEM) to determine the 3DNC structure, spectrophotometer FT-IR to determine drug interaction to 3DNC, high performance liquid chromatography (HPLC) to determine Famotidine in rabbit plasma. Conclusion: Three-dimensional nano-cellulose network has an involvement of the nano-sized cellulose fibers with three dimensional networks that are capable of loading Famotidine drug. How to Cite this Article Pubmed Style Mai VH, Nguyen XT, Lai PL, Do TL, Le TP. and Assessment of the absorption capability of famotidine to 3D-nano-cellulose SRP. 2020; 11(7): 309-313. doi:10.31838/srp.2020.7.48 Web Style Mai VH, Nguyen XT, Lai PL, Do TL, Le TP. and Assessment of the absorption capability of famotidine to 3D-nano-cellulose http://www.sysrevpharm.org/?mno=127504 [Access: March 29, 2021]. doi:10.31838/srp.2020.7.48 AMA (American Medical Association) Style Mai VH, Nguyen XT, Lai PL, Do TL, Le TP. and Assessment of the absorption capability of famotidine to 3D-nano-cellulose SRP. 2020; 11(7): 309-313. doi:10.31838/srp.2020.7.48 Vancouver/ICMJE Style Mai VH, Nguyen XT, Lai PL, Do TL, Le TP. and Assessment of the absorption capability of famotidine to 3D-nano-cellulose SRP. (2020), [cited March 29, 2021]; 11(7): 309-313. doi:10.31838/srp.2020.7.48 Harvard Style Mai, V. H., Nguyen, . X. T., Lai, . P. L., Do, . T. L. & Le, . T. P. (2020) and Assessment of the absorption capability of famotidine to 3D-nano-cellulose SRP, 11 (7), 309-313. doi:10.31838/srp.2020.7.48 Turabian Style Mai, Van Hung, Xuan Thanh Nguyen, Phuong Lien Lai, Thuy Linh Do, and Thi Phuong Le. 2020. and Assessment of the absorption capability of famotidine to 3D-nano-cellulose Systematic Reviews in Pharmacy, 11 (7), 309-313. doi:10.31838/srp.2020.7.48 Chicago Style Mai, Van Hung, Xuan Thanh Nguyen, Phuong Lien Lai, Thuy Linh Do, and Thi Phuong Le. Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. Systematic Reviews in Pharmacy 11 (2020), 309-313. doi:10.31838/srp.2020.7.48 MLA (The Modern Language Association) Style Mai, Van Hung, Xuan Thanh Nguyen, Phuong Lien Lai, Thuy Linh Do, and Thi Phuong Le. Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. Systematic Reviews in Pharmacy 11.7 (2020), 309-313. Print. doi:10.31838/srp.2020.7.48 APA (American Psychological Association) Style Mai, V. H., Nguyen, . X. T., Lai, . P. L., Do, . T. L. & Le, . T. P. (2020) and Assessment of the absorption capability of famotidine to 3D-nano-cellulose Systematic Reviews in Pharmacy, 11 (7), 309-313. doi:10.31838/srp.2020.7.48