Deuteration of Alkenes with NaBD4/AcOD in Pre-Sence of Pd on Carbon

Proceedings(2019)

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Abstract
Activated alkenes such as cinnamates and chalcones can easily be converted to 2,3-dideuterio-arylpropionates and dideuteriochalcones, respectively, by the action of NaBD4, AcOD in the presence of Pd on carbon. Toluene or benzene was used as solvent. It was shown that Pd on carbon was necessary for the reaction to proceed. Deuterium addition experiments were also carried out with NaBD4, AcOD, D2O in the presence of Pd on carbon
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Key words
alkenes,nabd4/acod,carbon,pre-sence
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