Scalable Synthesis of Β-Lactamase Inhibitor QPX7728 by Sequential Nickel-Catalyzed Boron Insertion into a Benzofuran Substrate and Enantioselective Cyclopropanation of the Resulting Vinylboronate
Organic Process Research & Development（2021）
Key words
boron insertion,Ni catalysis,enantiosclectirc cyclopropanation,chiral auxiliary,vinylboronate
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