A smart probe for simultaneous imaging of the lipid/water microenvironment in atherosclerosis and fatty liver
Chemical Communications(2022)
摘要
A smart lipid droplet specific fluorescent probe (LDs-DM) with dual-emission in water (706 nm) and oil (535 nm) under single-excitation was prepared for revealing the ultra-structure of the aqueous and lipidic microenvironment in living cells, fatty liver tissues and atherosclerotic plaques without fluorescence emission crosstalk. This work is expected to provide inspiration for designing a novel probe with color switching ability.
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关键词
fatty liver,atherosclerosis,smart probe,lipid/water microenvironment
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