Severe Anemia Caused by Gastric Antral Vascular Ectasia and Autoimmune Gastritis

Kazuhiro Ota,Yosuke Mori,Hironori Tanaka, Takahiro Murata,Taro Iwatsubo,Shimpei Kawaguchi,Yuichi Kojima,Noriyuki Nakajima,Akitoshi Hakoda,Noriaki Sugawara,Toshihisa Takeuchi,Kazuhide Higuchi

INTERNAL MEDICINE（2022）

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Abstract

An 80-year-old man presented to our hospital with general fatigue on exertion that had gradually worsened over 6 months. His blood test revealed severe anemia, and gastroscopy revealed findings consistent with gas-tric antral vascular ectasia (GAVE) and autoimmune gastritis. We diagnosed the patient with severe anemia caused by GAVE and autoimmune gastritis. The present case suggested that GAVE is triggered by autoim-mune gastritis, and the mechanism is likely related to hypergastrinemia. The reporting of this rare case may help elucidate the cause of GAVE, which is currently unknown.

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Key words

iron deficiency, vitamin B12 deficiency, gastric antral vascular ectasia, autoimmune gastritis, hypergastrinemia, severe anemia

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