Evaluation of polarity switching for untargeted lipidomics using liquid chromatography coupled to high resolution mass spectrometry
Journal of Chromatography B(2022)
摘要
•Polarity switching allows positive and negative ionization in the same experiment.•The performance of polarity switching was evaluated for untargeted lipidomics.•Polarity switching performs well for untargeted lipidomics.•Polarity switching reduces the time of analysis and material costs.
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关键词
Lipidomics,Untargeted mass spectrometry,Polarity switching,Positive/negative switching
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