A positron emission tomography radiomic signature for distant metastases risk in oropharyngeal cancer patients treated with definitive chemoradiotherapy

N Patrik Brodin,Christian Velten, Jonathan Lubin,Jeremy Eichler,Shaoyu Zhu, Sneha Saha,Chandan Guha,Shalom Kalnicki,Wolfgang A Tomé,Madhur K Garg,Rafi Kabarriti

Physics and Imaging in Radiation Oncology（2022）

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摘要

•The wavelet_LHL_GLDZM_LILDE feature was found to be associated with progression-free survival.•A binary radiomics risk score was strongly associated with distant metastases for patients with HPV p16-negtive disease.•Improved risk stratification could identify high-risk patients as potential candidates for adjuvant immunotherapy.

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关键词

Radiomics,Positron emission tomography,Oropharyngeal cancer,Risk stratification

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