Oral Intragastric DMBA Administration Induces Acute Lymphocytic Leukemia and Other Tumors in Male Wistar Rats.

Omar S El-Masry,Hussain Abdullah Alhawaj,Muaz O Fagere,Amani Y Owaidah,Aisha Alamri,Khaldoon Alsamman

Journal of experimental pharmacology（2022）

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摘要

These results suggest the pleiotropic potential of DMBA in the induction of multiple types of malignancies, including leukemia. This could be used as a model to validate therapeutic targets for leukemia and other induced malignancies.

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关键词

7, 12-dimethylbenz[a]-anthracene,DMBA,fibrosarcoma,leukemia,parotid gland

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