Tumour characteristics of screen-detected and interval cancers in the Flemish Breast Cancer Screening Programme: A mammographic breast density study

•In an organized mammography screening programme interval cancers have a worse prognostic tumour profile than screen-detected cancers.•Analysis of molecular subtype distributions versus breast density reveals a higher percentage of the triple-negative phenotype in low-density breasts.•The observations support arguments against the prolongation of screening intervals in low-density breasts.