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Itaconate and Itaconate Derivatives Target JAK1 to Suppress Alternative Activation of Macrophages.

Marah C. Runtsch,Stefano Angiari,Alexander Hooftman,Ridhima Wadhwa,Yanling Zhang,Yunan Zheng, Joseph S. Spina,Melanie C. Ruzek,Maria A. Argiriadi,Anne F. McGettrick,Rui Santalla Mendez,Alessia Zotta,Christian G. Peace, Aoife Walsh,Roberta Chirillo,Emily Hams,Padraic G. Fallon, Ranjith Jayamaran,Kamal Dua,Alexandra C. Brown,Richard Y. Kim,Jay C. Horvat,Philip M. Hansbro,Chu Wang,Luke A. J. O'Neill

Cell Metabolism（2022）

引用 141|浏览66
关键词
itaconate,macrophages,M2 macrophage,Jak-STAT,immunometabolism,Krebs cycle
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