The Role of Extracellular Non-coding RNAs in Atherosclerosis

Journal of Cardiovascular Translational Research(2022)

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摘要
Atherosclerosis (AS) is a complex chronic inflammatory disease that leads to myocardial infarction, stroke, and disabling peripheral artery disease. Non-coding RNAs (ncRNAs) directly participate in various physiological processes and exhibit a wide range of biological functions. The present review discusses how different ncRNAs participate in the process of AS in various carrier forms. We focused on the role and potential mechanisms of extracellular ncRNAs in AS and examined their potential implications for clinical treatment.
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关键词
Non-coding RNAs (ncRNAs), Extracellular, Circulation, Extracellular vesicles (EVs), Atherosclerosis (AS), Arteriosclerotic cardiovascular disease (ASCVD)
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