SARS-CoV-2 Exposure Investigations Using Genomic Sequencing Among Healthcare Workers and Patients in A Large Academic Center.

Leigh Smith,C Paul Morris, Morgan H Jibowu,Susan Fallon,Stuart C Ray,Sara E Cosgrove,Melanie S Curless,Valeria Fabre,Sara M Karaba,Lisa L Maragakis,Aaron M Milstone,Anna C Sick-Samuels,Polly Trexler,Heba H Mostafa,Clare Rock

Infection control and hospital epidemiology（2022）

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摘要

SARS-CoV-2 transmissions among healthcare personnel (HCP) and hospitalized patients are challenging to confirm. Investigation of infected persons often reveals multiple potential risk factors for viral acquisition. We combined exposure investigation with genomic analysis confirming two hospital-based clusters. Prolonged close contact with unmasked, unrecognized infectious, individuals was a common risk.

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