Pro-resolving therapies as potential adjunct treatment for infectious diseases: Evidence from studies with annexin A1 and angiotensin-(1-7)
Seminars in Immunology(2022)
Abstract
•Resolution of inflammation is an active process mediated by molecules usually referred to as pro-resolving mediators.•AnxA1 and Ang-(1-7) have been shown to decrease the severity of tissue damage in various models of infection.•These molecules decrease inflammation while maintaining or enhancing the ability of the host to deal with infection.•There is potential for translating preclinical data with AnxA1 and Ang-(1-7) to patients with various infectious diseases.
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Key words
Infection,Resolution pharmacology,Angiotensin-(1-7),Annexin A1,Virus,Bacteria
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