The Utility of Discharge Antibiotics in Pediatric Perforated Appendicitis Without Leukocytosis

Christina M Theodorou,Su Yeon Lee,Yemi Lawrence,Payam Saadai,Shinjiro Hirose,Erin G Brown

Journal of Surgical Research（2022）

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摘要

Modification of a pediatric perforated appendicitis clinical practice guideline to discontinue antibiotics on discharge with a normal WBC without left shift was effective in decreasing antibiotic duration. This was associated with an increase in SSIs on univariate analysis, which did not persist on multivariable analysis and requires further investigation.

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关键词

Pediatric appendicitis,Perforated appendicitis,Leukocytosis,Left shift,Antibiotics,Clinical practice guideline

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