Towards individualized monitoring of cognition in multiple sclerosis in the digital era: A one-year cohort study

Ka-Hoo Lam,Ioan Gabriel Bucur,Pim Van Oirschot,Frank De Graaf,Hans Weda,Eva Strijbis,Bernard Uitdehaag,Tom Heskes,Joep Killestein,Vincent De Groot

Multiple Sclerosis and Related Disorders（2022）

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摘要

•Frequent cognition tests in the ambulant setting could enhance clinical assessment.•Weekly smartphone tests enable higher temporal resolution and individual curve fits.•Curve fitting improves the detection of statistically reliable change in cognition.•Thus enabling the remote monitoring of cognition on the individual patient-level.

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关键词

Multiple sclerosis,Cognition,Outpatient monitoring,Smartphone,Digital technology,Patient-specific modeling

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