Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France
CLINICAL INFECTIOUS DISEASES(2022)
摘要
A returned traveler to Uganda presented with a Plasmodium falciparum kelch13 A675V mutant infection that exhibited delayed clearance under artesunate therapy. Parasites were genetically related to recently reported Ugandan artemisinin-resistant A675V parasites. Adequate malaria prevention measures and clinical and genotypic surveillance are important tools to avoid and track artemisinin resistance.
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关键词
Plasmodium falciparum, kelch13, artemisinin resistance, East Africa, whole-genome sequencing
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