精准医疗时代重新审视胆管癌的诊治

World Chinese Journal of Digestology(2017)

Cited 0|Views5
No score
Abstract
胆管癌(cholangiocarcinoma,CCA)是一类相对少见的胆系恶性肿瘤.目前极其不良的预后源于对其分子发病机制认识不足和有效治疗方法的匮乏.精准医疗计划的提出和大量分析癌症基因组数据,有助于对肿瘤分子发病机制深入了解以及发现潜在治疗靶点.近年来研究证实肝内、外CCA无论流行病学、病因、分子发病机制、诊治方法和预后都存在较大差异,将CCA按肝内CCA、肝门部CCA和远端CCA分类并深入研究各型生物学特性是迈向精准个体化医疗战略中重要的第一步.相信随着基础和临床研究的深入,CCA各型组学信息的获得、整合和以此为据实施的精准靶向治疗,将改善患者预后,提高总生存率.
More
Translated text
Key words
Intrahepatic cholangiocarcinoma,Perihilar cholangiocarcinoma,Distal cholangiocarcinoma,Molecular aberrations,Precision medicine
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined