RNA targets of TDP-43: Which one is more important in neurodegeneration?
Translational Neurodegeneration(2022)
摘要
Nuclear loss and cytoplasmic aggregation of TDP-43 is the most common shared pathological feature of fronto-temporal dementia(FTD)and amyotrophic lateral scle-rosis(ALS),a motor neuron disease also known as Lou Gehrig's disease[1].
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