Molecularly Guided Drug Repurposing for Cholangiocarcinoma: An Integrative Bioinformatic Approach

Simran Venkatraman,Brinda Balasubramanian,Pisut Pongchaikul,Rutaiwan Tohtong,Somchai Chutipongtanate

Genes（2023）

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摘要

This study proposes the use of the immune-oncogenic gene signature to identify high-risk CCA patients. Future preclinical and clinical studies are required to elucidate the therapeutic efficacy of the molecularly guided drugs as the adjunct therapy, aiming to improve the survival outcome.

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cholangiocarcinoma,connectivity map,drug repurposing,drug–gene network,immune-oncogenic gene signature,survival analysis,transcriptomics

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