Multilevel Regulation of Protein Kinase CδI Alternative Splicing by Lithium Chloride
Molecular and Cellular Biology（2021）
Abstract
Lithium chloride (LiCl) is commonly used in treatment of mood disorders; however, its usage leads to weight gain, which promotes metabolic disorders. Protein kinase C delta (PKCδ), a serine/threonine kinase, is alternatively spliced to PKCδI and PKCδII in 3T3-L1 cells.
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Key words
protein kinase,alternative splicing,lithium
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