Chondroblastoma affecting the mandibular condyle: a case report and immunohistochemical analysis

Chondroblastoma is a rare benign cartilaginous tumor, representing less than 1% of all bone tumors. It was first described by Jaffe and Lichtenstein in 1942. Chondroblastomas in the skull and facial bones are quite rare, and lesions in the mandibular condyle are rarer still. A 32-year-old man was referred presenting with a discrete increased volume on the right condyle, slightly symptomatic, with several months of evolution. The patient reported temporomandibular joint dysfunction and hyaluronic acid application. Imaginologic examination revealed an osteolytic lesion affecting the right condyle. An incisional biopsy was performed, and microscopy was consistent with chondroblastoma. The immunohistochemical analysis revealed positivity for vimentin and S100, whereas CD68 and CD163 highlighted osteoclast-like giant cells and macrophages. Ki-67 was <2%. To the best of our knowledge, this is the eighth chondroblastoma case affecting the mandibular condyle. Chondroblastoma is a rare benign cartilaginous tumor, representing less than 1% of all bone tumors. It was first described by Jaffe and Lichtenstein in 1942. Chondroblastomas in the skull and facial bones are quite rare, and lesions in the mandibular condyle are rarer still. A 32-year-old man was referred presenting with a discrete increased volume on the right condyle, slightly symptomatic, with several months of evolution. The patient reported temporomandibular joint dysfunction and hyaluronic acid application. Imaginologic examination revealed an osteolytic lesion affecting the right condyle. An incisional biopsy was performed, and microscopy was consistent with chondroblastoma. The immunohistochemical analysis revealed positivity for vimentin and S100, whereas CD68 and CD163 highlighted osteoclast-like giant cells and macrophages. Ki-67 was <2%. To the best of our knowledge, this is the eighth chondroblastoma case affecting the mandibular condyle.