The role of cAMP signaling in the regulation of interleukin-33 production by RAW264.7 macrophages in response to various doses of lipopolysaccharide

Background: Recent reports suggest that interleukin (IL)-33 plays pathogenic roles in various inflammatory disorders including allergic diseases. However the mechanism underlying regulation of IL-33 production remains poorly understood. At present, we examined the role of cAMP signaling in the regulation of IL-33 production by RAW264.7 macrophages in response to various doses of lipopolysaccharide (LPS).