Interactions between microtubule-actin cross-linking factor 1 (MACF1) and Ca2+ during cell migration and cancer metastasis

Ting-Yu Lin,Feng-Chiao Tsai, Pei-Chin Hsu,Fei-Lin Chen

Proceedings for Annual Meeting of The Japanese Pharmacological Society（2018）

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摘要

Ca2+ signaling plays an important role in cell migration and cancer metastasis, but how calcium coordinates other structural components to regulate cell migration machinery and cancer progression remains unclear. Searching for novel calcium regulatory molecules and discovering the interaction between calcium and these molecules may help us understand how calcium controls proper cell motility.

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关键词

macf1,metastasis,cell migration,cancer,microtubule-actin,cross-linking

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