Voltammetric determination of Pd(II) using the decrease of 5-hydroxyimino-4-imino-1,3-thiazolidin-2-one cathode peak

Derivatives of azolidones are widely use in pharmaceutical and medicinal chemistry. They are characterized low toxicity and wide spectrum of biological activities: antifungal, anticancer, antibacterial, antiviral, antituberculosiсal, anti-inflammatory, hypoglycemic, hepatoprotective action. These substances are perspective analytical reagents for spectrophotometric and voltammetric determination of platinum metals. The possibility of the voltammetric determination of palladium (II) ions using a new azolidone derivative – 5-hydroxyimino-4-imino-1,3-thiazolidin-2-one has been shown. The dependence of cathode peaks voltammetric characteristics of 5-hydroxyimino-4-imino-1,3-thiazolidin-2-one in the absence and in the presence of palladium (II) ions on the acidity of the medium was investigated. It was established that the complexation of palladium (II) ions with 5-hydroxyimino-4-imino-1,3-thiazolidin-2-one is observed throughout the studied acidity range of the medium: from pH 1.0 to pH 10.0. The complexation of palladium (II) with 5-hydroxyimino-4-imino-1,3-thiazolidin-2-one occurs with the participation of oxime and imino groups, which is indicated by a decrease of the cathode peaks of organic reagent in the presence of palladium (II) ions. Optimal conditions were selected, and sensitive methods of voltammetric determination of palladium (II) ions were developed by the decrease of the cathode peak of oxime group at the background of acetate buffer solution at pH 6.0 (LOD = 7.2·10 -7 M), as well as at NaCl background at pH 2.0 (LOD = 1.1·10 -6 M). The selectivity towards the ions of concomitant metals was investigated for the method of voltammetric determination of palladium (II) at pH 2.0 on a background of NaCl, as well as the successful approbation of the developed method in the analysis of alloys Yb 2 Pd 2 Ga and Yb 40 Pd 38 Sn 22 was carried out. Keywords: palladium, voltammetric determination, azolidone, oxime.