Фокусированный ультразвук высокой интенсивности: тепловой нагрев и разрушение биологической ткани

The paper presents the results of a numerical study of the processes of heating and destruction of biological tissue by a series of high-intensity focused ultrasound (HIFU) pulses generated by a multi-element transducer. Tumor treatment programs that differ in the spatial localization of focal points in the tissue (Archimedes spiral, “square” spiral), the number of pulses and the delay between pulses are considered. A significant effect of the parameters of a series of pulses and the perfusion process on the boundaries of the proceeded region in the considered range of moderate radiation intensities was established. It is shown that over time, the process of heat propagation in tissue becomes quasispherical and weakly depends on the type of ablation program. The possibility of using this process property to optimize the protocols of HIFU medical procedures is discussed.