Endoscopic follow-up of high-risk adenocarcinoma arising from barrett’s esophagus (be), results of 120 patients from the dutch barrett expert center cohort

Aims After radical endoscopic resection(ER) of esophageal adenocarcinoma(EAC) in BE with high-risk(HR) features, optimal management is unclear. This concerns three groups: HR-T1a-EAC (poorly(G3)/undifferentiated(G4) cancer a/o lymphovascular invasion(LV+)); low-risk(LR) T1b-EAC (submucosal invasion< 500um, no G3/G4, no LV); HR-T1b EAC (invasion>500um, G3/G4, a/o LV+). Endoscopic follow-up(FU) to detect lymph node metastases(N+) at a curable stage is considered in selected cases, however, optimal FU strategy is unclear. Aim was to evaluate outcomes of endoscopic FU in all patients treated by radical ER for HR-T1a or T1b-EAC.