Optimization of F-18-fluorocholine PET/CT protocol for the detection of hyperfunctioning parathyroid tissue in patients with hyperparathyroidism

Ziel/Aim Accurate preoperative localization of hyperfunctioning parathyroid tissue in patients with hyperparathyroidism (HPT) is a prerequisite for performing minimally invasive surgery. Recent studies demonstrated the high diagnostic value of F-18-fluorocholine (FCH) PET/CT in the preoperative localization of parathyroid adenomas, though the optimal time of imaging after intravenous application of FCH has yet to be established. The aim of this study was to determine an adequate FCH PET/CT protocol and to explore the relationship between FCH PET/CT and laboratory parameters in patients with HPT.