Assessment of myocardial deformation parameters in patient with microvascular angina. longitudinal study

Aim. The aim of the study was to determine the benefit of myocardial deformation parameters in the course of treatment in patients with microvascular angina. Methods. The study included 141 patients who underwent coronary artery angiography, coronary artery flow assessment, MD imaging. Patients were divided into two groups: expected and confirmed MVA. After 2 years, echocardiography was repeated. Results. Significant improvements in MVA dynamics were seen in radial myocardial strain (21.92±11.01→33.11±13.57) and radial systolic (1.96→3.07), early (–2.19→–2.57) and late (–1.44→–1.83) diastolic strain rates (SR). Confirmed MVA showed statistically significant improvements in longitudinal myocardial strain (–17.93→19.72), longitudinal systolic (–1.15±0.18→–1.21±0.18), and late (–1.15±0.30→–1.25±0.27) diastolic SR. Conclusions. Longitudinal strain, systolic and late diastolic SR could be useful oninvasive method to assess treatment efficacy in patients with microvascular angina. Changes in radial myocardial strain, radial systolic and diastolic early and late SR are more common in the presence of the expected MVA. Their diagnostic value is not fully explored and should be the subject of ongoing work.