Synthetic, Natural Derived Lipid Nanoparticles and Polymeric Nanoparticles Drug Delivery Applications

In modern therapeutic field, the delivery of drugs to the desired site is a crucial bottleneck that needs to be addressed for efficacy and potency of the administrated drug. The recent advancements in the field of nanotechnology has enabled researchers to deliver the drug and other diagnostic agents without unfavorable effect in human. Though drug delivery system (DDS) is highly advantageous, the clinical success rate depends on the appropriate carrier molecules which precisely recognize the target site for the release of drug and its biocompatibility. To overcome this concern both synthetic and naturally derived lipid-based nano carriers are the preeminent option as it is biocompatible, non-toxic, enhances the bioavailability of poorly absorbed drugs, drug release modulation flexibility, improved drug loading capacity and stability. Similarly, several bioinspired synthetic polymeric nanomaterials shown advantage of controlled release with less toxic effects, better encapsulation and grand bioavailability. In this chapter, we discussed about the broad spectrum of lipids (synthetic and natural) and polymeric nanoparticles (synthetic and natural) for potential drug delivery applications.