Synthesis of Polyfluorinated KRN7000 Analogues and Biological Implications
The 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery（2019）
Abstract
KRN7000 is a synthetic glycosphingolipid developed as an anticancer drug candidate, whichupon association with the CD1d protein activates NKT cells. [...]
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Key words
α-GalCer,KRN7000,glycosphingolipid,fluorine,glycolipid antigens
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