Mp03-14 relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine chemistry

You have accessJournal of UrologyStone Disease: Basic Research & Pathophysiology I (MP03)1 Apr 2019MP03-14 RELATIONSHIP OF ENDOSCOPIC LESIONS OF THE RENAL PAPILLA WITH TYPE OF RENAL STONE AND 24 H URINE CHEMISTRY Xavier Arnau Sabate Arroyo*, Enrique Pieras Ayala, Felix Grases Freixedas, Jose Luis Bauza Quetglas, Jorge Guimerá Garcia, and Pedro Piza Reus Xavier Arnau Sabate Arroyo*Xavier Arnau Sabate Arroyo* More articles by this author , Enrique Pieras AyalaEnrique Pieras Ayala More articles by this author , Felix Grases FreixedasFelix Grases Freixedas More articles by this author , Jose Luis Bauza QuetglasJose Luis Bauza Quetglas More articles by this author , Jorge Guimerá GarciaJorge Guimerá Garcia More articles by this author , and Pedro Piza ReusPedro Piza Reus More articles by this author View All Author Informationhttps://doi.org/10.1097/01.JU.0000554946.72194.e5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: Our purpose was to study the relationship between the type of endoscopic calcification in the renal papilla (Randall's plaque, intratubular calcification, papillary crater) with stone chemistry and 24-h urine chemistry. METHODS: This was a prospective study of 41 patients (age range: 18 to 80 years) undergoing retrograde intrarenal surgery (RIRS) for renal lithiasis (mean stone size: 15.3 mm ± 7.2 mm). We classified injuries of the renal papilla as Randall's plaque, tubular calcification, or papillary crater. The renal calculi were classified as uric acid, calcium oxalate monohydrate, calcium oxalate dihydrate, or calcium phosphate. A 24 h urine analysis of calcium, oxalate, citrate, and pH was performed in all patients. Each papillary endoscopically injury was analyzed and correlated with the type of stone and urine chemistry. Fisher's exact test and Student's t-test were used to determine the significance of differences. A p-value below 0.05 was considered statistically significant. RESULTS: The most common injury was tubular calcification (78%), followed by Randall's plaque (58%) and papillary crater (39%). There was no significant relationship between Randall's plaque with the type of stone. However, there were significant relationships between the type of stone and intratubular calcification (p = 0.025) and papillary crater (p = 0.041), in that COD and calcium phosphate stones were the most common types in both groups. There was also a significant relationship between the papillary crater and hypercalciuria (p = 0,036), between Randall's plaque and hypocitraturia (p=0,005) and papillary crater and hypooxaluria (p=0,024). None of the other differences were statistically significant. CONCLUSIONS: Tubular calcification is the most common injury in patients with advanced renal lithiasis. Tubular calcification and papillary crater most often have COD and calcium phosphate stones. Hypercalciuria has positive associations with tubular calcification. Hypocitraturia has positive associations with Randall's plaque. Tubular calcification and papillary crater may represent the same type of papillary injury. Source of Funding: none Sant Iscle de Vallalta, Spain; Palma de Mallorca, Spain© 2019 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 201Issue Supplement 4April 2019Page: e26-e26 Advertisement Copyright & Permissions© 2019 by American Urological Association Education and Research, Inc.MetricsAuthor Information Xavier Arnau Sabate Arroyo* More articles by this author Enrique Pieras Ayala More articles by this author Felix Grases Freixedas More articles by this author Jose Luis Bauza Quetglas More articles by this author Jorge Guimerá Garcia More articles by this author Pedro Piza Reus More articles by this author Expand All Advertisement PDF downloadLoading ...