Lung Transplant Recipients with Severe Primary Graft Dysfunction Developed Decreased Transplant Arteriosclerosis in Humanized Mice Models

Introduction: Primary graft dysfunction (PGD) is the main cause of early mortality after lung transplantation (LTx). Multiple mechanisms have been described, but the link between PGD, T cell priming and immune answer has not been defined. In humanized mice, we studied leukocytes from human lung recipients undergoing PGD with different kinetics and their impact on rejection of artery grafts.