Postoperative CSF Leaks following Endoscopic Anterior Skull Base Surgery: Risk Factors and Management

Objective: Postoperative cerebrospinal fluid leak following endoscopic anterior skull base surgery is one of the leading causes of postoperative morbidity. The factors associated with increased incidence of postoperative CSF leaks have not been well described. In this study, we analyze data from a 10-year period of endoscopic anterior skull base surgery in our institution to identify characteristics associated with increased risk of postoperative cerebrospinal fluid leak. Management of these leaks is also described.