Impact of circle of Willis anatomic variations on anterior circulation aneurysm rupture

Introduction: The rupture risk assessments for intracranial aneurysms are generally based estructuraly on size, morphology and topography of the aneurysm. However, hemodynamics plays a fundamental role in aneurismal rupture. There is a definite correlation between the anomalies of circle of Willis and aneurysm formation, especially asymmetric proximal segments of anterior circulation. But, whether this association is related to intracranial aneurysm rupture, isn’t well known.