Advanced Esthesioneuroblastoma Management: 20 Years Single-Center Experience

Introduction: Esthesioneuroblastoma is an uncommon tumor derived from the olfactory neuroepithelium that has a propensity for cranial base involvement through bone erosion and tumor extension to the anterior cranial fossa. It was first described in 1924 and has only around one thousand cases reported in the literature, which compromise the evaluation of the optimal treatment management.