Biochemical Changes Investigated by Psoroptic Mange Infestation in Buffaloes

The present study was executed on fifty buffaloes ( Bubalusbubalus ), aged 1-3years, suffering from signs of pruritus and alopecia throughout the perio d from January to December 2015. Upon parasitological enquiry, they were proved to be inf ested by Psoroptes species. The changes in the sero- biochemical parameters were compared in two groups, infested group and non infested healthy group, each of 30 buffaloes. The following parameters were assessed: serumtotal protein (TP), serum albumin (ALB), blood urea nitrogen (BUN), creatinine levels , serum enzymatic activities levels as glutamic-- pyruvic transaminase (GPT ), glutamic oxaloacetic t ransaminase (GOT), alkaline phosphastase (ALP), and lactate dehydrogenase (LDH), Oxidative and anti oxidative biomarkers as malondialdehyde (MDA), Glutathione S-transferase (GST), superoxide dismuta se (SOD) and catalase (CAT), inflamatory parameters as C- reactive protein (CRP), pro inflam matory cytokines (IL6) and tumor necrosis factor (TNF). The results concluded a significant differen ce in the serum constituents (P<0.05) between the infested buffaloes and the non-infestedones.