Long-term outcomes in the Multimodal Treatment study of Children with ADHD (the MTA)

James M. Swanson, L. Eugene Arnold,Peter S. Jensen,Stephen P. Hinshaw, Lily T. Hechtman, William E. Pelham, Laurence L. Greenhill,C. Keith Conners,Helena C. Kraemer,Timothy Wigal, Benedetto Vitiello,Glen R. Elliott, Howard B. Abikoff,Betsy Hoza, Jeffrey H. Newcorn, Karen Wells,Marc Lerner,Brooke S. G. Molina,Jeffery N. Epstein,Elizabeth B. Owens,James Waxmonsky,Desiree W. Murray,Margaret H. Sibley,John T. Mitchell,Arunima Roy

Oxford Medicine Online(2018)

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Abstract
This chapter describes the long-term outcomes in the Multimodal Treatment study of ADHD (MTA), which began in 1994 and ended in 2014. First, we provide a short history of the origin of the MTA. Second, we review the design as a 14-month randomized clinical trial and the transition to a long-term follow-up. Third, we present findings from 12 key publications describing outcomes in four stages of the MTA from childhood to adulthood. Fourth, we discuss how the final adult assessments of the MTA address critical issues about symptomatic persistence of ADHD, functional outcomes outside the parental home, and cost-benefit analyses of residual effects of treatment with medication.
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