Stereocontrolled Formal Synthesis of Platencin

European Journal of Organic Chemistry(2018)

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摘要
A stereocontrolled formal synthesis of platencin was accomplished in 11 steps from a bromophenol derivative, with an overall yield of 13 %. The intermolecular Diels–Alder reaction of masked o ‐benzoquinone and an aldol condensation were the key steps in the construction of the tricyclic core of platencin.
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Polyketide Biosynthesis
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