Metabolic Syndrome and Neurodegenerative Diseases

Neurodegenerative diseases are progressive disorders that affect central nervous system and gradually worsen over time. Despite many experimental and clinical studies being performed, no effective cure has been found yet. Protein aggregation, excitotoxicity, neuronal death, inflammation, mitochondrial dysfunction, oxidative stress and metabolic syndrome are among the major role players in neurodegeneration. Increasing evidence demonstrates that metabolic syndrome is interrelated with many neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's Diseases.