Vascular complications of dysglycaemia

The dysglycaemic cardiovascular continuum is defined as a state of long-lasting insulin resistance, compensatory hyperinsulinaemia, and early glucometabolic impairment clustering with concomitant cardiovascular risk and the development of macrovascular disease prior to the diagnosis of type 2 diabetes. There is indeed a strong biological relation between hyperglycaemia, insulin resistance, and vascular disease.