Non-invasive, Simultaneous Quantification of Vascular Oxygenation, Glucose Uptake and Mitochondria Membrane Potential in a Flank Tumor Model

Caigang Zhu,Hannah Martin,Martin Li,Brian Crouch,Amy Martinez,Gregory Palmer,Mark Dewhirst,Nimmi Ramanujam

Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS)（2018）

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摘要

For the first time, we performed simultaneous in vivo spectroscopy of tissue hemoglobin, 2-NBDG, and TMRE in a preclinical model, to successfully capture vascular and metabolic parameters in vivo in solid tumors.

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关键词

mitochondria membrane potential,glucose uptake,vascular oxygenation,membrane potential,non-invasive

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