T104. Plasma Interleukin-1 Beta is Associated With Deficits in Spatial Recognition Memory in Youth With Bipolar Spectrum Disorders

Deficits in youth with Bipolar Spectrum Disorders (BSD) include chronic emotion dysregulation, affect recognition, cognitive decline and sensorimotor deficits. Dysregulated levels of cytokines, associated with BSD pathophysiology, have also been associated with cognitive deficits including impaired spatial recognition memory (SRM) in individuals with BSD. This study is an evaluation of the association between the proinflammatory cytokine interleukin-1 beta (IL-1β) and SRM in youths with BSD.